Principal Scientist, Downstream Process Development in Westborough, Massachusetts at Pall

Date Posted: 10/5/2019

Job Snapshot

Job Description

Job ID: LIF004378

About Us

Find what drives you on a team with a 70+ year history of being recognized for discovery, determination, and innovation.   As a global leader in high-tech filtration, separation, and purification, Pall Corporation thrives on helping our customers protect people. Our portfolio is broad, so if your interests lie along the spectrum of Life Sciences to Industrial, you’ll find a rewarding role here.  Our career opportunities are as diverse as our products and they are all focused on creating better lives and a better planet.  At Pall, we believe that innovation is our legacy, our privilege, and our destiny. If that resonates with you, join us! 


Pall Corporation of Westborough is seeking a Principal Scientist, Downstream Process Development. Pall’s Process Development Services group provides our customers with best in class, innovative solutions for their downstream processing needs. 

You will be a subject matter expert (SME) on manufacturing downstream processes for gene therapy and biologic applications working with new game changing technologies as well as provide scientific leadership to a small team of purification scientists reporting to the PDS lab Senior Manager. We are a fun, dedicated, hardworking, science driven organization, if this sounds like you, apply today!
Responsibilities include: 
  • Mentoring, executing, developing, providing guidance and managing workloads for the associates and being part of the hands on purification team. 
  • Lead planning and execution of experiments for Pall downstream process development services including, depth filtration, chromatography I, polish chromatography TFF testing, sterile filtration, AKTA systems, or other DSP automation systems
  • Prepare project reports, by combining all data from a specific project from multiple individuals and making recommendations to clients on the direction of the project
  • Close interaction with the customer, presenting rational behind the experiment plan and experimental results
  • Prepare detailed protocols for execution for practical work and batch manufacturing records for process transfer to GMP manufacturing
  • Assist the project manager with administrative functions – preparation of report drafts, budget tracking, draft proposals, BoM
  • Plan and execute experiments for DSP, experience with process development and scale-up of DSP unit-operations
  • Troubleshoot customer data, look for efficiencies and recommend right products and equipment to achieve best results
  • Train and support DSP activities in Portsmouth, UK PDS Lab
  • Perform analytical assays, possibly including gels, ELISA, qPCR, SDS-Page
  • Analyze project results and summarize for discussion with team. Make recommendations for further optimization

Job Requirements


  • Bachelors in biological science / chemical engineering & minimum of 7+ years of experience in protein purification or MS in biology / chemical engineering & 5+ years of experience in protein purification or a PhD with 3+ industrial relevant purification experience 
  • Experience with purification with chromatography strength of viral particles (gene therapy and/or vaccine fields) or Monoclonal antibodies
  • Small scale purification development as well as large scale experience
  • A good understanding of product purification mechanisms
  • Prior experience compiling information into technical reports
  • Supervisory experience including performance management and development of employees
  • Ability to travel as needed.
Diversity & Inclusion
At Danaher, we are dedicated to building and sustaining a truly diverse and inclusive culture. These are not just words on a page—Diversity and Inclusion is a top priority for the company, and it ties deeply to each of our core values. Danaher Corporation and all Danaher Companies are equal opportunity employers that evaluate applicants without regard to race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law.

Danaher Corporation Overview

Danaher is a global science & technology innovator committed to helping our customers solve complex challenges and improve quality of life worldwide. Our world class brands are leaders in some of the most demanding and attractive industries, including life sciences, medical diagnostics, environmental and applied solutions. Our globally diverse team of 71,000 associates is united by a common culture and operating system, the Danaher Business System, which serves as our competitive advantage. We generated $19.9B in revenue last year. We are ranked #162 on the Fortune 500 and our stock has outperformed the S&P 500 by more than 5,200% over 25 years.
At Danaher, you can build a career in a way no other company can duplicate. Our brands allow us to offer dynamic careers across multiple industries. We're innovative, fast-paced, results-oriented, and we win. We need talented people to keep winning. Here you'll learn how DBS is used to shape strategy, focus execution, align our people, and create value for customers and shareholders. Come join our winning team.
Danaher is committed to competitive compensation that typically has key components including base salary, variable annual incentive compensation based on personal and company performance, and long-term incentive.